Original Article

Analysis of HIV RNA Results in HIV/AIDS Patients


  • Kadriye Kart Yaşar
  • H. Ahmed Kehribar
  • Havva Kaşıkçı
  • Nermin Cebeci
  • Filiz Pehlivanoğlu
  • Gönül Sengöz
  • Hayat Kumbasar Karaosmanoğlu

Med Bull Haseki 2014;52(2):80-83


In this study, we retrospectively evaluated the demographic features and the results of human immunodeficiency virus (HIV) RNA testing in 65 cases with HIV infection.


We analyzed HIV RNA values in patients investigated using real time polymerase chain reaction (RT-PCR) between June and September 2010. HIV RNA levels of less than 500 copies/ml in patients receiving highly active antiretroviral therapy (HAART) were considered virological response.


Of 65 patients aged between 23-80 years old (median: 42±12), 55 were male; and six of them were diagnosed over one year and followed up in different medical centers. In fifteen patients (25%), who were aged between 23 and 69 years and were newly diagnosed with HIV, HIV RNA levels were found to be between 481 and 1.497.088 copies/ml (median 215.554 copies/ml). Of 44 patients followed up in our clinic, 39 (89%) were receiving HAART and their HIV RNA levels ranged between 0 and 680.842 copies/ml, and viral load was <500 copies/ml in 25 of 39 (64%) cases. This rate was obtained in 22 of 33 (67%) subjects who were on HAART for more than six months.


Of our patients, 25% were new diagnosed. Of all patients followed up, 89% were on antiretroviral therapy and the virological response was 64%. This result may be related with patient incompliance and antiretroviral resistance. HIV RNA level which is an important follow-up parameter may be helpful for confirming new cases and predicting antiviral resistance and virological failure.

Keywords: HIV/AIDS, HIV RNA, PCR, viral load, virological response

Full Text (Turkish)